Lumida
/MDGL
⌘K
Madrigal Pharmaceuticals Inc

Madrigal Pharmaceuticals Inc

MDGL
$553.48USD+1.46%+7.95 today

MARKET CAP

12.8B

P/E (TTM)

FWD P/E

1,499.3x

DAY RANGE

$536 – $560

52W RANGE

$286
$615

AI Summary

Stalk
StalkMedium

In a Stage 2 advancing environment with supporting LT and MT uptrends and a recent momentum breakout, the structure remains bullish. However, price is extended above rising EMAs and extreme overbought on RSI and options metrics, so execution is deferred into pullbacks around the confluence of the 9/21 EMAs rather than chasing the current stretch.

  • ResDifera net sales $1.1B+ last 12 months; Q1 sales $311M (+127% YoY).
  • Active patients 42,250, +150% YoY, indicating strong adoption momentum.
  • Q1 2026 operating loss $94.4M vs $73.2M prior year, widening margin strain.
Full analysis →
Insider Trades44 trades
DateSideTickerInsiderRoleSharesPriceMkt Cap52W High52W LowValue% ChgRuleAI View
Jun 1, 2026SellMDGLDavid SoergelChief Medical Officer1,042$495.74$12.8B-10.00%+93.23%$516.6K-9.41%10b5-1Stalk
May 18, 2026SellMDGLDavid SoergelChief Medical Officer844$515.90$12.8B-10.00%+93.23%$435.4K-7.08%Stalk
Mar 6, 2026SellMDGLShannon T KelleyGeneral Counsel360$431.94$12.8B-10.00%+93.23%$155.5K-2.05%Stalk
Mar 6, 2026SellMDGLCarole HuntsmanChief Commercial Officer419$431.94$12.8B-10.00%+93.23%$181.0K-2.32%Stalk
Mar 6, 2026SellMDGLWilliam John SiboldPresident and CEO1,663$431.94$12.8B-10.00%+93.23%$718.3K-0.91%Stalk
Mar 6, 2026SellMDGLMardi DierEVP and CFO1,982$430.87$12.8B-10.00%+93.23%$854.0K-1.20%10b5-1Stalk
Mar 2, 2026SellMDGLMardi DierEVP and CFO1,183$427.21$12.8B-10.00%+93.23%$505.4K-11.33%Stalk
Jan 26, 2026SellMDGLCarole HuntsmanChief Commercial Officer910$493.78$12.8B-10.00%+93.23%$449.3K-4.61%10b5-1Stalk
Jan 26, 2026SellMDGLWilliam John SiboldPresident and CEO1,577$492.42$12.8B-10.00%+93.23%$776.5K-1.05%Stalk
Jan 20, 2026SellMDGLShannon T KelleyGeneral Counsel692$497.36$12.8B-10.00%+93.23%$344.2K-3.83%10b5-1Stalk
Dec 4, 2025SellMDGLWilliam John SiboldPresident and CEO2,400$575.34$12.8B-10.00%+93.23%$1.4M-1.57%Stalk
Dec 2, 2025SellMDGLMardi DierEVP and CFO8,346$414.99$12.8B-10.00%+93.23%$3.5M+0.00%10b5-1Stalk
Nov 21, 2025SellMDGLCarole HuntsmanChief Commercial Officer1,958$553.11$12.8B-10.00%+93.23%$1.1M-1.66%10b5-1Stalk
Sep 9, 2025SellMDGLWilliam John SiboldPresident and CEO7,279$445.63$12.8B-10.00%+93.23%$3.2M-6.63%Stalk
Aug 21, 2025SellMDGLWilliam John SiboldPresident and CEO7,616$400.18$12.8B-10.00%+93.23%$3.0M-3.34%10b5-1Stalk
Aug 18, 2025SellMDGLShannon T KelleyGeneral Counsel1,304$367.81$12.8B-10.00%+93.23%$479.6K-1.67%10b5-1Stalk
Mar 10, 2025SellMDGLMardi DierSVP and CFO258$323.04$12.8B-10.00%+93.23%$83.3K-2.41%10b5-1Stalk
Mar 5, 2025SellMDGLRobert E. WaltermireSenior VP, Chief Pharma Dev.28,226$214.41$12.8B-10.00%+93.23%$6.1M+0.00%Stalk
Mar 3, 2025SellMDGLShannon T KelleyGeneral Counsel415$335.00$12.8B-10.00%+93.23%$139.0K-5.39%10b5-1Stalk
Mar 3, 2025SellMDGLCarole HuntsmanChief Commercial Officer1,834$325.98$12.8B-10.00%+93.23%$597.8K-2.09%10b5-1Stalk
Mar 3, 2025SellMDGLMardi DierSVP and CFO1,961$324.96$12.8B-10.00%+93.23%$637.2K-11.84%10b5-1Stalk
Feb 28, 2025SellMDGLRobert E. WaltermireSenior VP, Chief Pharma Dev.1,227$341.07$12.8B-10.00%+93.23%$418.5K-13.85%Stalk
Jan 24, 2025SellMDGLRobert E. WaltermireSenior VP, Chief Pharma Dev.103$335.24$12.8B-10.00%+93.23%$34.5K-2.04%Stalk
Jan 24, 2025SellMDGLCarole HuntsmanChief Commercial Officer347$335.24$12.8B-10.00%+93.23%$116.3K-3.22%Stalk
Jan 24, 2025SellMDGLRebecca TaubPres., R&D, and CMO648$335.24$12.8B-10.00%+93.23%$217.2K-0.14%Stalk
Jan 24, 2025SellMDGLWilliam John SiboldPresident and CEO1,584$335.24$12.8B-10.00%+93.23%$531.0K-2.83%Stalk
Jan 17, 2025SellMDGLShannon T KelleyGeneral Counsel277$273.41$12.8B-10.00%+93.23%$75.7K-3.47%Stalk
Jan 17, 2025SellMDGLRobert E. WaltermireSenior VP, Chief Pharma Dev.442$273.41$12.8B-10.00%+93.23%$120.8K-8.04%Stalk
Jan 17, 2025SellMDGLRebecca TaubPres., R&D, and CMO1,689$273.41$12.8B-10.00%+93.23%$461.8K-0.37%Stalk
Nov 21, 2024SellMDGLCarole HuntsmanChief Commercial Officer688$316.92$12.8B-10.00%+93.23%$218.0K-6.00%Stalk
Sep 9, 2024SellMDGLWilliam John SiboldPresident and CEO6,363$243.83$12.8B-10.00%+93.23%$1.6M-10.22%Stalk
Jun 14, 2024SellMDGLRobert E. WaltermireSenior VP, Chief Pharma Dev.3,800$183.54$12.8B-10.00%+93.23%$697.5K+0.00%Stalk
Jun 12, 2024SellMDGLRobert E. WaltermireSenior VP, Chief Pharma Dev.4,000$186.46$12.8B-10.00%+93.23%$745.8K+0.00%Stalk
May 21, 2024SellMDGLRobert E. WaltermireSenior VP, Chief Pharma Dev.1,036$231.34$12.8B-10.00%+93.23%$239.7K-15.85%Stalk
Apr 8, 2024SellMDGLRebecca TaubPres., R&D, and CMO5,352$127.72$12.8B-10.00%+93.23%$683.5K+0.00%10b5-1Stalk
Apr 3, 2024SellMDGLRebecca TaubPres., R&D, and CMO147,776$126.68$12.8B-10.00%+93.23%$18.7M+0.00%10b5-1Stalk
Jan 16, 2024SellMDGLRobert E. WaltermireSenior VP, Chief Pharma Dev.550$243.92$12.8B-10.00%+93.23%$134.2K-9.71%Stalk
Jan 16, 2024SellMDGLBrian Joseph LynchSVP and General Counsel949$243.92$12.8B-10.00%+93.23%$231.5K-6.33%Stalk
Jan 16, 2024SellMDGLAlex G. HowarthChief Financial Officer1,067$243.92$12.8B-10.00%+93.23%$260.3K-7.11%Stalk
Jan 16, 2024SellMDGLRebecca TaubPres., R&D, and CMO1,546$243.92$12.8B-10.00%+93.23%$377.1K-9.34%Stalk
Dec 14, 2023SellMDGLRobert E. WaltermireSenior VP, Chief Pharma Dev.8,000$161.71$12.8B-10.00%+93.23%$1.3M+0.00%Stalk
Dec 12, 2023SellMDGLRobert E. WaltermireSenior VP, Chief Pharma Dev.7,600$155.37$12.8B-10.00%+93.23%$1.2M+0.00%Stalk
Dec 4, 2023SellMDGLBrian Joseph LynchSVP and General Counsel5,600$152.58$12.8B-10.00%+93.23%$854.5K+0.00%Stalk
Nov 29, 2023SellMDGLBrian Joseph LynchSVP and General Counsel14,000$137.62$12.8B-10.00%+93.23%$1.9M+0.00%Stalk